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The Health Report: Diet Drugs Gone Wild!

Mar 30 2006 by Kelly Mahan Jaramillo

Vote now!

Journalist Rachel Johnson reports in Vogue magazine this month about a new diet drug that has yet to be approved by the FDA; however, it has already gained attention from the New York Times, NPR, and most recently, as a plot point on the popular television show Boston Legal.

Drugmaker Sanofi-Aventis has created Rimonabant (the generic name) but it seems the brand name will be called Acomplia. Need we say more?

It has already been touted as the new "miracle" diet aid, but before everyone races to their doctor for a prescription, let's not forget Orlistat, which has earned the nickname "oily scat" due to a messy and rather unfortunate side effect in the bowel arena.

And who can forget the "Fen-Phen" fiasco of only a few years ago?

"You cannot compare the two," sputtered Dr. Doug Greene, M.D., vice president of regulatory development for Sanofi-Aventis. "It's not even apples and oranges....it's grapefruit and peas."

No, it is not a grapefruit and pea diet, or even a grapefruit and pea pill that will fill your stomach but has a side effect of sudden vomiting with no nausea warning.

No.

Acomplia is the first in a new class of drugs that blocks a pleasure receptor in the brain, the neurotransmitter endocannabinoid, so named because cannabis, a.k.a. marijuana, activates the same receptor. Remember smoking a joint, then polishing off three pints of Cherry Garcia ice cream? That was your endogenous cannabinoid system (EC, for short) flying into high gear. Acomplia does just the opposite on the EC system, giving one the "de-munchies."

In short, you will derive no pleasure from the taste of food, and voila! You will eat less. It is vitally important that we have less pleasure, and Acomplia is going to help us accomplish this.

The public is roaring for this new "miracle" diet drug, and rumor has it that it is not the FDA holding up the process. It has been overheard that who-knows-why-she-is-a-celebrity Nicole Richie has a basement full of the drug, and is not giving up one single pill.

Clearly, Acomplia works. Perhaps too well.

Something strange is going on inside the White House - does the Weapons of Mass Euphoria Team have the cure, or are they the culprits? Check out the reports from deep inside the WME.


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